Collection: Using wireless technology, we developed integrated and compact biosensor on an adhesive body patch that is able to collect and transmit data related to dopamine and cortisol in real-time using an apple or android phone.
Cortisol and dopamine are two key biomolecules secreted in the human body. Cortisol is the body’s main stress hormone, while dopamine is a key neurotransmitter due to its function in human metabolism, cardiovascular, central nervous, renal, and hormonal systems. An abnormal level of cortisol results in physiological illnesses, such as Cushing's syndrome and Addison's disease, mental illnesses, such as depression and post-traumatic stress disorder (PTSD), respectively. An abnormal level of dopamine can lead to many neurological diseases/disorders such as dementia, schizophrenia, ADHD, epilepsy, Alzheimer’s, and Parkinson’s disease. To date, conventional colorimetric methods have been used for the detection of dopamine and cortisol outside of the body. However, these techniques are generally laborious, time-consuming, and expensive, which hinders the early diagnosis of several dopamine/cortisol-related diseases. To overcome these issues, we introduce fully integrated and compact flexible biosensors on patches equipped with wireless technology to automatically collect and transmit the data related to dopamine and cortisol concentrations in real-time without the need for additional equipment, reagents, or healthcare professionals.